0102030405
I-GMP-TL112 Anti-Human CD20 mAb Ukufakwa okuhlosiwe kwe-B cell apoptosis
I-CD20 iyingqamuzana ethile yesiginesha ebusweni be-lymphocyte B futhi ivezwa ngaphezu kuka-95% wama-lymphocyte B avamile noma ayingozi. Akukho ukuvezwa kwe-CD20 antigen kumaseli we-hematopoietic stem, amaseli azala, nezinye izicubu ezijwayelekile. Iqukethe ama-amino acid angama-297 anesisindo samangqamuzana angama-33 kD. I-CD20 ayinakho ukwenziwa kwangaphakathi noma ukuchithwa kweseli ngemuva kokubopha nge-anti-CD20 mAb, okuyi-antigen efanelekile ekwelapheni izifo ezihlobene ne-B lymphocyte. I-Anti-CD20 mAb ingabulala iningi lamaseli e-lymphoma aveza ama-molecule e-CD20 namaseli B avamile. Amaseli B azalwa nawo awathintwa i-anti-CD20 mAb futhi angakha kabusha inani lamaseli e-B. Ngakho-ke, ama-anti-CD20 monoclonal antibodies aya ngokuya esetshenziswa ekwelapheni izifo ezihlobene nama-B cell
| Ama-Cytokines | |
| QC Testing Ubumsulwa | > 90 % njengoba kunqunywa i-SDS-PAGE. |
| I-Endotoxin | |
| Ukwakhiwa | Ihlinzekwa njengesixazululo esihlungiwe esingu-0.22μm ku-PBS, PH 7.4 |
| Ama-Antibodies e-Monoclonal | |
| Umsebenzi webhayoloji | Izinga lokubophezela nge-PBMCs |
| Expression Host | Amaseli we-CHO |
| Ukuhlanzwa: | Iphrotheni A ehlanjululwe ku-cell culture supernatant. |
| Ukuzinza Nesitoreji | Izinyanga ezingama-24 ku-2℃ kuye ku-8℃. Gwema imijikelezo yokuqhwaza ephindaphindiwe. |
| Isithupha | Imininingwane yefayela |
 | I-GMP-TL502_SDS.pd |
| GMP-TL502_Product Sheet.pdf |