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I-Anti-Human CD28 mAb GMP-TL102 Idala ukuhlukaniswa nokwanda kwamaseli e-T
Uhlolojikelele Lomkhiqizo
I-Anti-Human CD28 mAb (GMP TL102) idizayinelwe ukubangela ukuhlukaniswa kwamaseli e-T nokwanda. Le anti-monoclonal antibody ihlinzeka ngendlela eqinile yokuthuthukisa izimpendulo ze-T cell, iyenze ibe ithuluzi elibalulekile kukho kokubili ucwaningo nezinhlelo zokusebenza zomtholampilo.
Izici Eziyinhloko
● Ukuqaliswa Kweseli T: Kudala ngokunamandla ukuhlukaniswa nokwanda kwamaseli e-T, okubalulekile ezifundweni ze-immunological.
● Ukuthobelana kwe-GMP: Kwenziwe ngokuhambisana namazinga e-GMP, iqinisekisa ikhwalithi ephezulu nokuvumelana.
● Ukuhlanzeka Okuphezulu: Iqinisekisa ukungcola okuncane kanye nokucaciswa okuphezulu kwe-CD28, okuthuthukisa ukwethembeka kokuhlolwa.
● Ukusetshenziswa Okuhlukahlukene: Ifanele ukusetha okuhlukahlukene kokuhlola, okuhlanganisa isiko lamaseli kanye nocwaningo lwe-immunotherapy.
Izinhlelo zokusebenza
● I-T Cell Research: Ilungele izifundo ezigxile ekusebenzeni kwe-T cell, ukusayina, nokusebenza.
● Ukuthuthukiswa Kwe-Immunotherapy: Isekela ukuthuthukiswa kwe-T cell-based immunotherapies.
● Izivivinyo Zomtholampilo: Ifanele ukusetshenziswa ocwaningweni lomtholampilo oludinga ama-reagents ebanga le-GMP.
Imininingwane kanye nokupakishwa
• Ukucaciswa: Kutholakala ngosayizi abahlukahlukene ukuze kuhlangatshezwane nezidingo zokuhlola ezihlukene, ezihlanganisa i-100μg, 500μg, ne-1mg.
• Ukupakishwa: Kuhlinzekwa ngoketshezi oluyinyumba noma impushana e-lyophilized ukuze kube lula ukuyisebenzisa futhi igcinwe.
Isitoreji Nokuzinza
• Isitoreji: Gcina ku-2-8°C ukuze usetshenziswe isikhathi esifushane noma -20°C ukuze uthole isitoreji sesikhathi eside ukuze ugcine ukuqina nokusebenza kwe-antibody. Gwema imijikelezo yokuqhwaza ephindaphindiwe ukuze uvimbele ukuwohloka.
• Ukuzinza: Izinzile ekulondolozeni isikhathi eside ngaphansi kwezimo ezinconyiwe, okuqinisekisa ukusebenza okuthembekile ezinhlelweni zocwaningo.
Imiyalo Yokusetshenziswa
1.Nciphisa i-antibody endaweni efanele noma endaweni ngaphambi kokuyisebenzisa.
2.Lungisa futhi usebenzise isixazululo ngokuvumelana nezidingo zokuhlola ukuze uzuze imiphumela enembile nekwazi ukukhiqiza kabusha.
3.Landela izivumelwano ezifanele zohlelo oluhlosiwe, njenge-flow cytometry, i-immunohistochemistry, noma ukuhlola okusebenzayo.
Izixwayiso
• Lo mkhiqizo uhloselwe ukusetshenziswa ucwaningo kuphela futhi awulungele ukuxilonga imitholampilo noma izinhlelo zokusebenza zokwelapha.
• Phatha i-antibody ngokwemiyalelo enikeziwe ukuze ugcine ukusebenza kwayo nobuqotho.
• Nganoma yiziphi izinkinga noma imibuzo mayelana nomkhiqizo, sicela uxhumane nethimba lethu losekelo lobuchwepheshe.
| Ama-Antibodies e-Monoclonal | |
| Izinhlelo zokusebenza | Indlela encibilikayo: ukugxila okungu-500 ng/mL kuyanconywa, lapho amaseli e-T angenziwa asebenze futhi amaseli e-CD3⁺CD56⁺T anganwetshwa kakhulu. |
| Umsebenzi webhayoloji | Izinga lokubophezela ngamaseli e-Jurkat akufanele libe ngaphansi kuka-90%. |
| Indlela yokumboza: | I-10 mL ye-PBS buffer (5μg/mL anti-human CD3) ifakwa kuflask ye-T75 ku-4°C ngobusuku. Sicela ususe i-PBS bese ugeza iflaski ngosawoti omncane izikhathi ezintathu ngaphambi kokuyisebenzisa. |
| I-Endotoxin | |
| Expression Host | Amaseli e-Mouse Hybridoma |
| Ukwakhiwa | Ihlinzekwa njengesixazululo esihlungiwe esingu-0.22μm ku-PBS, PH 7.4. |
| Ukuhlanzwa: | Iphrotheni A ehlanjululwe ku-cell culture supernatant |
| QC Testing Ubumsulwa | > 95 % njengoba kunqunywa i-SDS-PAGE |
| Ukuzinza Nesitoreji | Izinyanga ezingama-24 ku-2℃ kuye ku-8℃. Gwema imijikelezo yokuqhwaza ephindaphindiwe. |
| Isithupha | Imininingwane yefayela |
 | I-GMP-TL102_SDS.pdf |
| GMP-TL102_Product Sheet.pdf |