Iyo Kugadziridza Champion mune Yepamusoro-Tembiricha Mamiriro! T&L Biotechnology Inotangisa Zviri pamutemo New-Generation Thermostable bFGF Protein
Basic Fibroblast Growth Factor (bFGF), inhengo yefibroblast kukura factor mhuri, inokonzeresa kusaina nzira dzekutapurirana nekusunga uye kumisa mareceptor pane tarisiro.T Sero surfaces. bFGF inoronga kuwanda kwemhando dzakasiyana-siyana dzemasero, kusanganisira endothelial masero, neurons, chondrocytes, masero akatsetseka emhasuru, melanocytes, uye adipocytes. Pamusoro pezvo, bFGF inobatanidzwa mune zvipenyu maitiro akadai sero kuzvivandudza, kusiyanisa, kusimudzira, kugadzirisa matishu, uye kuberekwa patsva. Sechinhu chakakosha pakukura kwesero, bFGF inoshandiswa zvakanyanya muin vitro tsika yemhando dzakasiyana siyana.
Zvidzidzo zvinoratidza kuti bFGF haina kugadzikana pasi pemamiriro emuviri, ine hafu yehupenyu hwemaawa angangoita 8 mumammalian cell tsika. Kudzikama kwemafuta uye hupfupi hafu yehupenyu hwebFGF inotungamira kune zvipingamupinyi musero tsika, inoda kugara ichikura chinhu chekuwedzera kana zuva nezuva kutsiva kwepakati. Iyo thermostable bFGF protein, yakagadzirwa kuburikidza nekugadziriswa kweiyo bFGF yechisikigo, inogadzirisa dambudziko iri. Iyo inochengetedza yakasimba biological chiitiko cheyakasikwa bFGF ichiwana yakawedzera kugadzikana kwekupisa, kuchengetedza kurongeka kwechimiro uye kuita kweprotein pane yakakura tembiricha renji.
Embryonic yevanhu Stem Cells (hESCs) uye induced pluripotent stem masero (iPSCs) ane mukana wekusiyanisa mumhando dzese somatic cell. Munguva ye in vitro tsika yehESCs uye iPSCs, bFGF yakakosha kuchengetedza stem cell pluripotency. Tsvagiridzo inoratidza kuti hESCs yakasimudzwa ne thermostable bFGF inoita makoroni asina kupatsanurwa nekukurumidza (Fig. 1A) uye anoratidza kuwedzera kwekuwedzera kwemazinga panguva yenguva refu tsika (Fig. 1B). Zvimwe zvidzidzo zvinoratidza kuti thermostable bFGF inosimudzira hESC kuwedzera uku ichitsigira kutaura kwepluripotency mamaki (semuenzaniso, OCT4, SOX2, KLF4), ichisimbisa kugona kwayo kuchengetedza hESC pluripotency-chinhu chakakosha chekushandiswa kwesero tsika.
A: Mamiriro ekukura ehESCs paZuva 2 pasi pekudyisa-yemahara tsika mamiriro ane akasiyana bFGF akasiyana.
B: Kuenzaniswa kwemazinga ekukura kwesero panguva yekuenderera kwetsika neWT-bFGF (wild-type) kana TS-bFGF (thermostable) pasi pemamiriro asina feeder.
Product Launch
Recombinant Human bFGF Protein (Heat Stable)
Product Features
- Thermostable
- Kuchena Kwepamusoro (>90%)
- High Activity
- Yakaderera Endotoxin (
- Sterile
- Mycoplasma-Yemahara
Product Performance
pplication Scenario
Kana yawedzerwa kuPSC tsika yepakati, kutsiva kwepakati kunogona kuitwa mazuva maviri ese.
Sezvakaratidzwa mumufananidzo 5, T & L's Recombinant Human bFGF Protein (GMP-TL901) uye Thermostable bFGF yakashandiswa kuAMMS® Pluripotent Stem Cell Medium (AS-35) yePSC tsika. Pakati pekuwedzera ne thermostable bFGF, zuva nezuva kana mamwe-mamwe-mamwe-mazuva epakati shanduko yakavandudza zvakanyanya nhamba dzekoloni uye saizi zvichienzaniswa neyakajairwa bFGF. Zvinonyanya kukosha, kushanda kwesero hakuna kuratidza musiyano wakakosha pakati pezuva nezuva uye mamwe-mamwe-mamwe-mazuva maprotocol ane thermostable bFGF, ichisimbisa kukodzera kwayo kwemutengo-inoshanda iPSC tsika.
Kufarira kuedza yedu New-Generation Thermostable bFGF Protein?
Bata isu nhasi kuti tikumbire sampuli yemahara uye uzvionere mabhenefiti ega patsvagiridzo yako!
T&L Biotechnology Co., Ltd inotarisa pakutsvagisa nekusimudzira kwekumusoro, GMP-giredhi zviwanikwa uye reagents dzesero uye. Gene Therapy (CGT). Isu takazvipira kupa yakakwana mhinduro kune vatengi veCGT kuburikidza neyakajeka chigadzirwa uye sevhisi zvinopihwa. Zvigadzirwa zvedu zvinosanganisira kupatsanurwa kwesero uye activation magnetic beads, eukaryotic/prokaryotic recombinant proteins, serum-free medium, cell culture kits, nezvimwe.
Isu tinoshandisa rabhoritari yekutsvagisa nekusimudzira uye 3,200-square-metres GMP-level workshop yakachena. Zvivakwa izvi zvinosanganisira mapuratifomu ekuparadzanisa masero magineti bead kusimudzira, eukaryotic uye prokaryotic protein expression engineering, uye serum-yemahara yepakati kusimudzira. Isu tinonamatira kune ese ISO 13485 uye ISO 9001 Quality Management System Standards. Pamusoro pezvo, zvimwe zvezvigadzirwa zvedu zvine FDA DMF mafirita.