0102030405
GMP-TL101 Anti-Human CD3 mAb Ganewar Antigen, watsa sigina da kunna T cell
Bayanin Samfura
Anti-Human CD3 mAb (GMP TL101) an ƙera shi don sauƙaƙe gano antigen, watsa sigina, da kunna tantanin halitta T. Wannan maganin rigakafi na monoclonal muhimmin sashi ne don duka bincike da aikace-aikacen asibiti waɗanda suka haɗa da magudin ƙwayoyin T.
Mabuɗin Siffofin
● Canjawar siginar: Ingantacciyar ƙaddamar da ƙaddamarwar antigen da watsa sigina, mai mahimmanci don kunna ƙwayoyin T.
● Ƙirƙirar GMP: Ana samarwa a ƙarƙashin tsauraran sharuɗɗan GMP don tabbatar da ingancin samfur da haɓakawa.
● Ƙayyadaddun Ƙwararren Ƙwararren Ƙwararren Ƙwararren Ƙwararren Ƙwararren Ƙwararren Ƙwararren Ƙwararren Ƙwararren Ƙwararren Ƙwararren Ƙwararren Ƙwararren Ƙwararren Ƙwararren Ƙwararren Ƙwararren Ƙwararren Ƙwararren Ƙwararren Ƙwararren Ƙwararren Ƙwararren Ƙwararren Ƙwararren Ƙwararren Ƙwararren Ƙwararren Ƙwaƙwalwa na CD3 na Ƙadda ) , yana tabbatar da daidaitattun niyya da ƙananan abubuwan da aka kashe.
● Faɗakarwa mai faɗi: Ya dace da aikace-aikace daban-daban, gami da cytometry kwarara, al'adun tantanin halitta, da bincike na warkewa.
Aikace-aikace
● Binciken Immunological: Mahimmanci don nazarin siginar siginar T-cell (TCR) da hanyoyin kunnawa.
● Ci gaban warkewa: Taimako a cikin haɓakar hanyoyin kwantar da hankali na T cell, gami da CAR-T far.
● Nazarin Clinical: Ya dace da ka'idojin bincike na asibiti da ke buƙatar ingantacciyar inganci, ƙwayoyin rigakafin GMP masu dacewa.
Ƙayyadaddun bayanai da Marufi
● Takaddun bayanai:
Akwai a cikin masu girma dabam don dacewa da buƙatun gwaji daban-daban: 100μg, 500μg, da 1mg.
Matsayin inganci yana tabbatar da daidaito da aminci.
● Marufi:
An ba da shi azaman ruwa mara kyau ko lyophilized foda don sauƙin amfani da ajiya mai dacewa.
Kunshe don kiyaye mutunci da inganci yayin sufuri da sarrafawa.
Adana da Kwanciyar hankali
Adanawa
Don amfani na ɗan gajeren lokaci, adana a 2-8 ° C.
Don ajiya na dogon lokaci, kiyaye a -20°C don kiyaye kwanciyar hankali da aiki na antibody.
A guji maimaita daskarewa-narkewa don hana lalacewa.
Kwanciyar hankali
Yana kiyaye kwanciyar hankali a ƙarƙashin shawarar yanayin ajiya, yana tabbatar da ingantaccen aiki a aikace-aikacen bincike.
An tsara shi don karko, tabbatar da tasiri na dogon lokaci.
Umarnin don Amfani
Tsarma maganin rigakafi a cikin madaidaicin buffer ko matsakaici kafin amfani.
Shirya da amfani da mafita kamar yadda ake buƙata na gwaji don ingantacciyar sakamako da za a iya sakewa.
Bi ƙa'idodin da suka dace don aikace-aikacenku, ko cytometry na gudana ne, immunohistochemistry, ko ƙididdigar aiki.
Tsanaki
• Wannan samfurin an yi shi ne kawai don amfani da bincike kuma bai dace da binciken asibiti ko aikace-aikacen warkewa ba.
• Riƙe maganin rigakafi bisa ga umarnin da aka bayar don kiyaye aikinsa da amincinsa.
Don kowace matsala ko tambayoyi, tuntuɓi ƙungiyar tallafin fasaha don taimako.
• Haɓaka bincikenku tare da ingantattun ƙwayoyin rigakafin mu masu inganci. Don cikakkun bayanan samfur da goyan baya, ziyarci gidan yanar gizon mu.
| Monoclonal Antibodies | |
| Aikace-aikace | Hanyar mai narkewa: ana ba da shawarar maida hankali na 500 ng/mL, wanda a ƙarƙashinsa ana iya kunna ƙwayoyin T kuma ana iya faɗaɗa sel CD3⁺CD56⁺T sosai. |
| Ayyukan halittu | Adadin ɗauri tare da sel Jurkat bazai zama ƙasa da 90% ba. |
| Hanyar sutura: | 10 ml PBS buffer (5μg/ml anti-human CD3) ana sanya shi a cikin tulun T75 a 4°C na dare. Da fatan za a cire PBS kuma a wanke flask da gishiri a hankali sau uku kafin amfani. |
| Endotoxin | |
| Mai watsa shiri Magana | Kwayoyin CHO |
| Tsarin tsari | An kawo shi azaman 0.22μm tace bayani a cikin PBS, PH 7.4 |
| Tsarkakewa: | Protein A tsarkake daga tantanin halitta al'ada supernatant |
| Tsaftar Gwajin QC | > 95% kamar yadda SDS-PAGE ya ƙaddara |
| Kwanciyar hankali & Ajiya | 24 watanni a 2 ℃ zuwa 8 ℃. Guji maimaita daskarewa-narkewa |
| Babban yatsa | Bayanin fayil |
 | GMP-TL101_SDS.pdf |
| Takardar bayanan GMP-TL101.pdf |