0102030405
Anti-Human CD28 mAb GMP-TL102 Induces T cell differentiation and proliferation
Product Overview
Anti-Human CD28 mAb (GMP TL102) is designed to induce T cell differentiation and proliferation. This monoclonal antibody provides a robust method for enhancing T cell responses, making it an essential tool for both research and clinical applications.
Key Features
● T Cell Activation: Potently induces T cell differentiation and proliferation, critical for immunological studies.
● GMP Compliance: Manufactured in accordance with GMP standards, ensuring high quality and consistency.
● High Purity: Ensures minimal contaminants and high specificity for CD28, enhancing experimental reliability.
● Versatile Use: Suitable for various experimental setups, including cell culture and immunotherapy research.
Applications
● T Cell Research: Ideal for studies focusing on T cell activation, signaling, and function.
● Immunotherapy Development: Supports the development of T cell-based immunotherapies.
● Clinical Trials: Suitable for use in clinical research requiring GMP-grade reagents.
Specifications and Packaging
• Specifications: Available in various sizes to meet different experimental requirements, including 100μg, 500μg, and 1mg.
• Packaging: Supplied in sterile liquid form or lyophilized powder for ease of use and storage.
Storage and Stability
• Storage: Store at 2-8°C for short-term use or -20°C for long-term storage to maintain antibody stability and activity. Avoid repeated freeze-thaw cycles to prevent degradation.
• Stability: Stable for long-term storage under recommended conditions, ensuring reliable performance in research applications.
Instructions for Use
1.Dilute the antibody in an appropriate buffer or medium before use.
2.Prepare and use the solution according to experimental requirements to achieve accurate and reproducible results.
3.Follow appropriate protocols for the intended application, such as flow cytometry, immunohistochemistry, or functional assays.
Cautions
• This product is intended for research use only and is not suitable for clinical diagnostics or therapeutic applications.
• Handle the antibody according to provided instructions to maintain its activity and integrity.
• For any issues or inquiries regarding the product, please contact our technical support team.
| Monoclonal Antibodies | |
| Applications | Soluble method: the concentration of 500 ng/mL is recommended, under which T cells can be activated and CD3⁺CD56⁺T cells can be expanded significantly. |
| Biological activity | The binding rate with Jurkat cells shall not be less than 90%. |
| Coating method: | 10 mL PBS buffer (5μg/mL anti-human CD3) is placed in a T75 flask at 4°C overnight. Please remove the PBS and wash the flask with saline gently three times before use. |
| Endotoxin | < 0.01EU per μg of the protein as determined by the LAL method |
| Expression Host | Mouse Hybridoma cells |
| Formulation | Supplied as a 0.22μm filtered solution in PBS, PH 7.4. |
| Purification： | Protein A purified from cell culture supernatant |
| QC Testing Purity | > 95 % as determined by SDS-PAGE |
| Stability & Storage | 24 months at 2℃ to 8℃. Avoid repeated freeze-thaw cycles. |
| Thumb | File information |
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GMP-TL102_SDS.pdf |
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GMP-TL102_Product Sheet.pdf |